Sertraline Treatment of Nonresponders to Extended Cognitive-Behavior Therapy in Pediatric Obsessive-Compulsive Disorder

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Moderate Treatment Outcome with Sertraline ut not Cognitive - Behavior Therapy in Pediatric bsessive - Compulsive Disorder ohn

ackground: The presence of a comorbid tic disorder may predict a poorer outcome in the acute treatment of pediatric bsessive-compulsive disorder (OCD). ethods: Using data from the National Institute of Mental Health (NIMH)-funded Pediatric OCD Treatment Study (POTS) that ompared cognitive-behavior therapy (CBT), medical management with sertraline (SER), and the combination of CBT and ER (COMB),...

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Sertraline in the treatment of obsessive-compulsive disorder.

S everal lines of investigation support a serotonergic hypothesis for the pathophysiology and treatment of OCD. Clomipramine, a tricyclic antidepressant that is a potent serotonin uptake inhibitor, was the first pharmacologic treatment for OCD to be studied in large multicenter trials. The successful outcome of these studies resulted in marketing approval by the United States Food and Drug Admi...

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Cognitive-Behavioral Therapy of Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is characterized by the presence of obsessions and/or compulsions that consume time and significantly interfere with the individual's daily routines, work, family or social life, causing marked distress (American Psychiatric Association, 2002). Until the 1980s, OCD was considered a rare disorder. The ECA (Epidemiological Catchment Area) study estimated its pr...

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Cognitive behavioral therapy of obsessive-compulsive disorder

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ژورنال

عنوان ژورنال: Journal of Child and Adolescent Psychopharmacology

سال: 2015

ISSN: 1044-5463,1557-8992

DOI: 10.1089/cap.2015.0041